Diagnosis and staging
Tumour entity, histology, stage and disease extent form the clinical foundation.
Tumour biology
Molecular and pathological features can refine classification and therapeutic questions.
Treatment history
Previous lines of therapy, response, toxicity and reasons for discontinuation are important for evidence matching.
Clinical context
Performance status, organ function, comorbidities and patient goals affect applicability of evidence.
Medical notice: This content is for information and evidence orientation only and does not replace medical diagnosis or treatment decisions.