Principle
Liquid biopsy analyses tumour-associated material in body fluids.
CTC and ctDNA
CTCs are intact circulating cells; ctDNA consists of circulating DNA fragments.
Applications
Research and clinical applications include molecular characterisation, resistance mechanisms and longitudinal monitoring.
Limitations
Sensitivity and clinical meaning vary by method and tumour type.
Medical notice: This content is for information and evidence orientation only and does not replace medical diagnosis or treatment decisions.