KNOWLEDGE CENTRE

Biomarkers

Prognostic, predictive and longitudinal markers

Definition

Biomarkers are measurable biological characteristics.

Prognostic and predictive

Prognostic markers are associated with disease course; predictive markers may be associated with response to a treatment.

Method dependence

Interpretation depends on specimen, assay method and tumour entity.

No automatic conclusion

A positive marker does not automatically mean that a treatment is appropriate or available.

Medical notice: This content is for information and evidence orientation only and does not replace medical diagnosis or treatment decisions.